SUPERFICIAL AND DEEP VENOUS THROMBOSIS

  • SUPERFICIAL AND DEEP VENOUS THROMBOSIS


    SUPERFICIAL VENOUS THROMBOSIS (SVT):
    It is the formation of a thrombus (blood clot) in the superficial veins, usually associated with inflammation (thrombophlebitis). Commonly affects great and small saphenous veins.

    DEEP VENOUS THROMBOSIS (DVT):
    It is the formation of thrombus in the deep veins of the lower extremities, pelvis, or less commonly in the upper limbs. It poses a risk for pulmonary embolism if the clot dislodges.

    AYURVEDIC CORRELATION:
    Can be correlated with Siragata Vata or Sira Granthi as mentioned in classics.

    "рд╕рд┐рд░рд╛рдГ рд╕реНрдиреЗрд╣рд╛рджрд┐рднрд┐рдГ рд╢реБрджреНрдзрд╛рдГ рд╕рдореНрдкреНрд░рд╛рдкреНрддрд╛рдГ рд╕реНрд╡рд╛рд╕реНрдереНрдпрдорд╛рд╢реНрд░рдпрдГред
    рд╡рд┐рдмрджреНрдзрд╛рдГ рд╕реНрдпрд╛рддреНрддреБ рдпрддреНрд░ рд╕реНрдпрд╛рддреНрддрджрд╛ рджреЛрд╖реИрдГ рд╕рд┐рд░рд╛рдЧреНрд░рд╣рдГрее"

    тАФ Sushruta Samhita, Chikitsa Sthana 18/17


    ETIOPATHOGENESIS

    MODERN VIEW (VIRCHOWтАЩS TRIAD):

    1. Endothelial injury: Trauma, surgery, inflammation

    2. Stasis of blood flow: Immobilization, varicose veins

    3. Hypercoagulability: Genetic factors (Factor V Leiden), malignancy, pregnancy, oral contraceptives

    RISK FACTORS:

    • Prolonged immobility

    • Recent surgery or trauma

    • Malignancy

    • Pregnancy and postpartum

    • Oral contraceptive pills

    • Obesity

    • Smoking

    • Previous history of DVT

    • Varicose veins (more in SVT)

    AYURVEDIC ETIOLOGY (NIDANA):

    • Abhighata (trauma)

    • Ati-sthiraasana (prolonged sitting)

    • Avara vyayama (lack of exercise)

    • Snigdha guru bhojana leading to Srotorodha

    • Kapha and Vata vitiation causing obstruction in siras

    "рдЖрд╕рд┐рдирдГ рд╢рдпрдорд╛рдирд╢реНрдЪ рдпрдГ рд╕реНрдпрд╛рджрд▓реНрдкрд╡рд┐рдЪреЗрд╖реНрдЯрд┐рддрдГред
    рд╕ рд░рдХреНрддрдЧрдордиреЗ рджреЛрд╖рд╛рдиреН рд╕рдВрдкреНрд░рд╛рдкреНрдиреЛрддрд┐ рди рд╕рдВрд╢рдпрдГрее"

    тАФ Charaka Samhita, Chikitsa Sthana 28/202


    CLINICAL FEATURES

    SUPERFICIAL VENOUS THROMBOSIS (SVT):

    • Localized pain, tenderness along the superficial vein

    • Redness and warmth over the vein

    • Palpable cord-like vein

    • Swelling may be mild

    • Fever (if infective component present)

    DEEP VENOUS THROMBOSIS (DVT):

    • Swelling of the entire limb or part of limb

    • Deep aching pain, heaviness in leg

    • Warmth over affected area

    • Pitting oedema

    • Positive HomansтАЩ sign (pain on dorsiflexion of foot)

    • Dilated superficial veins (collaterals)

    AYURVEDIC LAKSHANA:

    • Shotha (Swelling)

    • Toda (Pricking pain)

    • Snayugata shula (Ligament pain)

    • Raga (Redness)

    • Shopha with Stambha (Stiffness)


    INVESTIGATIONS

    BLOOD TESTS:

    • D-dimer test: Elevated in DVT (not specific)

    • CBC to rule out infection

    • Coagulation profile (PT, aPTT, INR)

    IMAGING:

    • Doppler Ultrasound: Investigation of choice

    • Venography: Gold standard (rarely used now)

    • MRI/CT Venography: For pelvic vein thrombosis

    • ECG and Chest X-ray: If PE is suspected


    DIFFERENTIAL DIAGNOSIS

    FOR DVT:

    • Cellulitis

    • BakerтАЩs cyst

    • Ruptured popliteal cyst

    • Lymphoedema

    • Muscle tear or hematoma

    • Compartment syndrome

    FOR SVT:

    • Insect bite with phlebitis

    • Cellulitis

    • Thrombosed varicose vein

    • Lymphangitis


    COMPLICATIONS

    DVT:

    • Pulmonary embolism (life-threatening)

    • Post-thrombotic syndrome

    • Chronic venous insufficiency

    • Recurrent DVT

    SVT:

    • Extension into deep venous system

    • Skin pigmentation and ulceration

    • Varicosities


    MANAGEMENT

    MODERN MANAGEMENT

    ACUTE MANAGEMENT (DVT):

    • Anticoagulants: Heparin followed by Warfarin or DOACs (e.g., Apixaban, Rivaroxaban)

    • Compression stockings

    • Leg elevation and mobilization

    • Inferior vena cava (IVC) filter (in high-risk patients with contraindications for anticoagulants)

    SVT MANAGEMENT:

    • NSAIDs for pain and inflammation

    • Warm compresses

    • Local heparin gel

    • Anticoagulants if SVT is extensive or near sapheno-femoral junction

    SURGICAL OPTIONS:

    • Thrombectomy (rare)

    • Ligation of affected veins (in recurrent SVT)

    • Sclerotherapy or laser for varicosities


    AYURVEDIC MANAGEMENT

    SHODHANA CHIKITSA:

    • Virechana with Trivrit, Eranda taila for Kapha-Vata shaman

    • Raktamokshana (Siravyadha) in localised dushta rakta dushti

    "рд╕рд┐рд░рд╛рдореЛрдХреНрд╖рдгрдореБрддреНрддрдордВ рд░рдХреНрддрджреБрд╖реНрдЯреНрдпрд╛рдВ рд╡рд┐рдирд┐рд░реНрдгрдпреЗрддреНред"
    тАФ Sushruta Samhita, Sutra Sthana 14/36

    SHAMANA CHIKITSA:

    • Dashamoola kwatha, Punarnavadi kwatha

    • Guggulu preparations: Kaishora Guggulu, Yogaraja Guggulu

    • Rakta shodhaka dravyas: Manjistha, Sariva

    • Local application:

      • Sikta taila

      • Jatyadi taila

      • Lepa of Haridra, Daruharidra, Shigru, Arjuna churna in case of inflammation

    PATHYA-AHARAVIHARA:

    • Avoid heavy, unctuous, and kapha-aggravating foods

    • Encourage light diet, barley, horse gram

    • Regular mild exercise (after acute phase)

    • Avoid prolonged sitting or standing


    PROPHYLAXIS AND PREVENTION

    • Early mobilization after surgery or long travel

    • Use of compression stockings

    • Adequate hydration

    • Prophylactic anticoagulants in high-risk individuals

    • Lifestyle modifications like weight reduction, avoiding smoking and sedentary habits


    INTEGRATED APPROACH (AYURVEDA + MODERN)

    • Ayurveda can aid in long-term prevention and recovery by improving Agni, clearing Srotorodha, and enhancing Rakta shuddhi

    • Modern interventions are necessary in acute phase and life-threatening complications like PE

    • A holistic plan combining Shamana, Shodhana, Ahara-Vihara along with modern pharmacological and diagnostic protocols ensures better patient outcomes